Journal of Biology and Medicine: Open Access
Genetic Variation of Indian Camel (Camelus dromedarius) Breeds Using Mitochondrion COI Gene Analysis
Pramathadhip Paul1 Payal Pal, and Ena Ray Banerjee
Abstract
Mitochondrial cytochrome c oxidase subunit I (COI) gene is the most conservative protein-coding gene in the mitochondrial genome of different animals. Universal primers are used to amplify 710 bp fragment of the COI gene. In India, there are four different breeds of camel present in different region - Bikaneri, Kuchchhi, Jaisalmeri, and Mewari. The aim of this article is to phylogenetic study based on the COI sequence analysis of these diverse animals. There are two advantages to focus on COI gene a) Universal primer; b) COI shows greater range of phylogenetic signal. Compared to other genes which codes protein, third position nucleotides of the COI gene show highly base substitutions, and therefore suitable for highest rate of molecular evolution, greater than 12S or 16S rDNA analysis. We are also reporting likelihood values, functional divergence in amino acid changes and polymorphism among four camel breeds in India. We have identified some unique mutations in the individual breed in India and therefore divergent from the main species.
Keywords: COI gene; Phylogenetic; Camelus dromedaries
Journal Information
- Journal Name: Journal of Biology and Medicine: Open Access
- Journal Abbreviation: J Bio Med Open Access
- Journal Code: JBMOA
- Format of Publication: Online
- Frequency of Publication: Two Issue a Year
- Language: English
- Starting Year: 2020
- Subject: Biology, Medicine, Medical Sciences
- Review Process: Single-Blind Peer-Review by Referees
- Time to 1st Decision: 1 to 4 weeks from date of submission
- Time to Acceptance: 3 to 6 weeks, depending upon the required revision cycles
- Time to Publication: 1 to 2 weeks from date of final submission
- Editor-in-Chief: CHEE KONG YAP
Indexed and Abstracted In
