Journal of Biology and Medicine: Open Access
A Retrospective Review of 300 Case Reports, Quality of Life and Correlation With Biomarkers Related to Tumor Burden, in Advanced Cancer
M.A. Nezami, Steven Hager DO, and Armin Chaychain
Abstract
It is currently the tumor size measured by RECIST criteria that is considered an indication for objective response to any effective therapy in cancer, however in advanced solid tumors, this indicator has been debated recently as it fails to correlate with clinical response, quality of life and even overall survival. In this short but large sample size case review, we look into a meaningful potential substitute for such metrics, defined by surrogates of tumor burden, and correlate that with biomarkers that can be easily measured through blood sample. We suggest further studies to be considered to validate our findings and propose a shift in current clinical practice by further generation of hypothesis, based on our review
Journal Information
- Journal Name: Journal of Biology and Medicine: Open Access
- Journal Abbreviation: J Bio Med Open Access
- Journal Code: JBMOA
- Format of Publication: Online
- Frequency of Publication: Two Issue a Year
- Language: English
- Starting Year: 2020
- Subject: Biology, Medicine, Medical Sciences
- Review Process: Single-Blind Peer-Review by Referees
- Time to 1st Decision: 1 to 4 weeks from date of submission
- Time to Acceptance: 3 to 6 weeks, depending upon the required revision cycles
- Time to Publication: 1 to 2 weeks from date of final submission
- Editor-in-Chief: CHEE KONG YAP
Indexed and Abstracted In
